
publication
BMP signaling in the intestinal epithelium drives a critical feedback loop to restrain IL-13-driven tuft cell hyperplasia
Although Helminth infections are prevalent throughout the world, they are particular a...
The TEAM Hub draws on different disciplines and perspectives to investigate the role of the tissue microenvironment in disease
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to identify changes in biological tissues associated with disease before there is a significant disruption of tissue structure and function. We also need to streamline the development and testing of new therapeutics that can prevent or reverse tissue damage in chronic incurable diseases. The TEAM Hub is constructing a biologically inspired pipeline to generate a dynamic picture of the tissue microenvironment. Combining imaging approaches and 3D artificial tissue models, we investigate the effects of tissue structure on cellular functions, the mechanisms underlying changes in tissues and healing processes, and the factors that affect the body’s response to injuries and diseases.
The TEAM Hub is composed of experts from diverse areas, ranging from Health Sciences to Physics and from Engineering to Biology. Meet the team behind this ambitious research.

Check below for details about all research conducted within the TEAM Hub.
Research AreasFacilities
Check below for details about all research conducted within the TEAM Hub.
Training
By providing research opportunities and developing educational programs for the larger community, we are helping Ontario and, indeed, all of Canada build expertise in emerging but increasingly important areas of research.
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publication
Although Helminth infections are prevalent throughout the world, they are particular a...

publication
After birth, the epithelium that lines our gut transitions (or matures) so that it can...
publication
The paper establishes the phosphorylation of heterogeneous nuclear ribonucleoprotein A1...
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